{"id":2836,"date":"2026-07-16T15:35:09","date_gmt":"2026-07-16T20:35:09","guid":{"rendered":"https:\/\/laserlab.com.co\/?post_type=product&#038;p=2836"},"modified":"2026-09-09T14:16:58","modified_gmt":"2026-09-09T19:16:58","slug":"mots-c","status":"publish","type":"product","link":"https:\/\/laserlab.com.co\/en\/product\/mots-c\/","title":{"rendered":"MOTS-C"},"content":{"rendered":"<div style=\"border: 1.5px solid rgb(212, 212, 212); border-radius: 16px; padding: 8px 24px; margin-bottom: 16px;\"><div style=\"display: flex; gap: 8px; margin-bottom: 16px; width: 100%; align-items: center; padding-top: 16px;\"><img decoding=\"async\" src=\"https:\/\/laserlab.com.co\/imgs-new\/icon-specs.svg\" alt=\"icon-laserlab\" style=\"width: 20px; height: 20px; margin: auto 0px;\" title=\"MOTS-C\"><h4 style=\"margin: auto 0px; color: #2b5559;\"><strong>Technical Specifications<\/strong><\/h4><\/div><p style=\"color: #333333 !important;\"><\/p>\n<p><b>Presentation <\/b><span style=\"font-weight: 400;\">Vial de 10 mg de producto liofilizado<\/span><\/p>\n<p><b>Degree<\/b><span style=\"font-weight: 400;\">High-purity product for research use.<\/span><\/p>\n<p><b>Ingrediente activo<\/b><span style=\"font-weight: 400;\">: MOTS-C, un p\u00e9ptido an\u00e1logo sint\u00e9tico de alfa-MSH.<\/span><\/p>\n<p><\/p><\/div>\n<div style=\"border: 1.5px solid rgb(212, 212, 212); border-radius: 16px; padding: 8px 24px; margin-bottom: 16px;\"><div style=\"display: flex; gap: 8px; margin-bottom: 16px; width: 100%; align-items: center; padding-top: 16px;\"><img decoding=\"async\" src=\"https:\/\/laserlab.com.co\/imgs-new\/icon-star.svg\" alt=\"icon-laserlab\" style=\"width: 20px; height: 20px; margin: auto 0px;\" title=\"MOTS-C\"><h4 style=\"margin: auto 0px; color: #2b5559;\"><strong>To highlight<\/strong><\/h4><\/div><p style=\"color: #333333 !important;\"><\/p>\n<p><span style=\"font-weight: 400;\">Mejora la sensibilidad a la insulina.<\/span><\/p>\n<p><strong>Favorece la eficiencia energ\u00e9tica, que decrece con la edad.<\/strong><\/p>\n<p><\/p><\/div>\n<details style=\"margin-bottom: 16px; border-radius: 16px; box-shadow: rgb(212, 212, 212) 0px 1px 5px 0px; padding: 8px 16px;\"><summary style=\"cursor: pointer; display: flex; justify-content: space-between; align-items: center; padding-bottom: 8px; padding-top: 8px;\"><h5 style=\"margin: auto 0px; color: #2b5559;\">Standard mode of use<\/h5><div style=\"color: #f3987b;\">\u2795<\/div><\/summary><div style=\"padding: 8px 0px 8px 0px; border-top: 1px solid rgb(212, 212, 212);\"><\/p>\n<p><b>Reconstitution <\/b><span style=\"font-weight: 400;\">With bacteriostatic water according to the recommended volume. Shake until a homogeneous suspension is obtained.<\/span><\/p>\n<p><b>Conservation<\/b><span style=\"font-weight: 400;\"> Once reconstituted, keep away from light, refrigerated at 2-8 \u00b0C. Use within 30 days.<\/span><\/p>\n<p><b>Dosage<\/b><span style=\"font-weight: 400;\"> 200 a 1000 mcg al d\u00eda mediante incremento gradual. Consultar a un especialista.<\/span><\/p>\n<p><b>Duration: <\/b><span style=\"font-weight: 400;\">Inyecciones subcut\u00e1neas diarias durante 8\u201312 semanas, extensibles a 16.<\/span><\/p>\n<p><\/div><\/details>\n<details style=\"margin-bottom: 16px; border-radius: 16px; box-shadow: rgb(212, 212, 212) 0px 1px 5px 0px; padding: 8px 16px;\"><summary style=\"cursor: pointer; display: flex; justify-content: space-between; align-items: center; padding-bottom: 8px; padding-top: 8px;\"><h5 style=\"margin: auto 0px; color: #2b5559;\">Standard mode of use<\/h5><div style=\"color: #f3987b;\">\u2795<\/div><\/summary><div style=\"padding: 8px 0px 8px 0px; border-top: 1px solid rgb(212, 212, 212);\"><\/p>\n<p><span style=\"font-weight: 400;\">MOTS-c es un p\u00e9ptido derivado de la mitocondria (MDP) compuesto por 16 amino\u00e1cidos que act\u00faa como regulador metab\u00f3lico, principalmente mediante la activaci\u00f3n de AMPK (suplemento dietario). Los estudios precl\u00ednicos demuestran que mejora la sensibilidad a la insulina, promueve la oxidaci\u00f3n de la grasa, mejora la capacidad de ejercicio y contrarresta el deterioro metab\u00f3lico relacionado con la edad.<\/span><\/p>\n<p><\/div><\/details>\n<details style=\"margin-bottom: 16px; border-radius: 16px; box-shadow: rgb(212, 212, 212) 0px 1px 5px 0px; padding: 8px 16px;\"><summary style=\"cursor: pointer; display: flex; justify-content: space-between; align-items: center; padding-bottom: 8px; padding-top: 8px;\"><h5 style=\"margin: auto 0px; color: #2b5559;\">Who is it for?<\/h5><div style=\"color: #f3987b;\">\u2795<\/div><\/summary><div style=\"padding: 8px 0px 8px 0px; border-top: 1px solid rgb(212, 212, 212);\">\n<p><span style=\"font-weight: 400;\">En el \u00e1mbito de la medicina regenerativa y la investigaci\u00f3n en longevidad, se estudia por los siguientes beneficios:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Imita los beneficios metab\u00f3licos de la actividad f\u00edsica, mejora la sensibilidad a la insulina y la tolerancia al ejercicio.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Control de peso, ayuda en la recomposici\u00f3n corporal al promover la oxidaci\u00f3n de grasas y reducir la grasa visceral.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Protege contra la atrofia muscular, ayudando a preservar la masa magra.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Optimiza la creaci\u00f3n de nuevas mitocondrias, combatiendo la fatiga cr\u00f3nica y mejorando los niveles generales de energ\u00eda.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 16px;\"><\/div><\/details><\/span><\/p>\n<details style=\"margin-bottom: 16px; border-radius: 16px; box-shadow: rgb(212, 212, 212) 0px 1px 5px 0px; padding: 8px 16px;\"><summary style=\"cursor: pointer; display: flex; justify-content: space-between; align-items: center; padding-bottom: 8px; padding-top: 8px;\"><h5 style=\"margin: auto 0px; color: #2b5559;\">How does it work?<\/h5><div style=\"color: #f3987b;\">\u2795<\/div><\/summary><div style=\"padding: 8px 0px 8px 0px; border-top: 1px solid rgb(212, 212, 212);\"><\/p>\n<p><span style=\"font-weight: 400;\">MOTS-c funciona como una \u00abse\u00f1al metab\u00f3lica de estr\u00e9s\u00bb que ayuda a optimizar el uso de energ\u00eda durante el estr\u00e9s nutricional o el ejercicio. Su mecanismo principal es la activaci\u00f3n del AMPK mediante la inhibici\u00f3n del ciclo del folato, lo que provoca la acumulaci\u00f3n de AICAR (un an\u00e1logo del AMP). La AMPK activada convierte las c\u00e9lulas en un modo eficiente energ\u00e9ticamente, mejorando la absorci\u00f3n de glucosa, la oxidaci\u00f3n de \u00e1cidos grasos y la respiraci\u00f3n mitocondrial, mientras regula a la baja el almacenamiento de grasa y la gluconeog\u00e9nesis.<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">MOTS-c tambi\u00e9n puede translocarse al n\u00facleo celular bajo condiciones de estr\u00e9s y aumentar los genes antioxidantes y de respuesta al estr\u00e9s. Las investigaciones indican que MOTS-c tambi\u00e9n puede modular las v\u00edas mTOR e inflamatorias, contribuyendo a los efectos en la longevidad y la salud. Sus acciones se asemejan a las del ejercicio y la metformina a nivel celular, lo que la hace de gran inter\u00e9s para la investigaci\u00f3n de trastornos metab\u00f3licos, obesidad y envejecimiento.<\/span><\/p>\n<p><\/div><\/details>\n<details style=\"margin-bottom: 16px; border-radius: 16px; box-shadow: rgb(212, 212, 212) 0px 1px 5px 0px; padding: 8px 16px;\"><summary style=\"cursor: pointer; display: flex; justify-content: space-between; align-items: center; padding-bottom: 8px; padding-top: 8px;\"><h5 style=\"margin: auto 0px; color: #2b5559;\">Preguntas m\u00e1s frecuentes<\/h5><div style=\"color: #f3987b;\">\u2795<\/div><\/summary><div style=\"padding: 8px 0px 8px 0px; border-top: 1px solid rgb(212, 212, 212);\"><\/p>\n<p><b>\u00bfCu\u00e1les son las dosis que se manejan en los protocolos de estudio?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Las pautas de investigaci\u00f3n m\u00e9dica suelen citar entre 5 mg y 10 mg por semana. Frecuencia, algunos protocolos dividen esta dosis en 1 o 2 aplicaciones por semana (ej. 5 mg dos veces por semana). Ciertos estudios cl\u00ednicos de longevidad aplican una fase inicial donde se administran 10 mg tres veces por semana durante las primeras 2 semanas antes de bajar a la dosis de mantenimiento semanal. Los ciclos de estudio suelen durar de 8 a 12 semanas, seguidos de un periodo de descanso obligatorio de 4 a 8 semanas.<\/span><\/p>\n<p><b>\u00bfCu\u00e1l es el mejor momento del d\u00eda para aplicarlo?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Los investigadores sugieren aplicarlo por la ma\u00f1ana. Debido a que optimiza el uso de energ\u00eda celular, si se administra de noche podr\u00eda causar ligeras alteraciones en el sue\u00f1o en algunos sujetos.<\/span><\/p>\n<p><b>\u00bfCu\u00e1les son los efectos secundarios reportados?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Al no existir datos masivos en humanos, los reportes cl\u00ednicos preliminares mencionan, dolor en el sitio de inyecci\u00f3n. El MOTS-C es conocido por ser un p\u00e9ptido que puede arder o doler localmente durante la aplicaci\u00f3n. Se recomienda rotar los sitios de inyecci\u00f3n. Enrojecimiento o inflamaci\u00f3n local, sofocos transitorios, sensaci\u00f3n de calor o enrojecimiento facial que dura entre 15 y 45 minutos post-inyecci\u00f3n. N\u00e1useas leves o fatiga en los primeros d\u00edas debido al ajuste metab\u00f3lico.<\/span><\/p>\n<p><b>\u00bfQui\u00e9nes deben evitarlo estrictamente?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Deportistas profesionales: Est\u00e1 estrictamente prohibido por la WADA (Agencia Mundial Antidopaje) en la categor\u00eda de Moduladores Metab\u00f3licos. Da positivo en los controles de dopaje. En personas que usan medicamentos para la diabetes, al activar la v\u00eda AMPK (similar a la metformina), mejora dr\u00e1sticamente la sensibilidad a la insulina. Si se combina con insulina o f\u00e1rmacos hipoglucemiantes sin supervisi\u00f3n, existe riesgo de sufrir hipoglucemias severas (bajones dr\u00e1sticos de az\u00facar). Mujeres embarazadas o en lactancia debido a la nula evidencia de seguridad.<\/span><\/p>\n<p><\/div><\/details>","protected":false},"excerpt":{"rendered":"[descripcion_corta_producto]<span style=\"font-weight: 400;\">El MOTS-c es un p\u00e9ptido natural codificado por el ADN mitocondrial que act\u00faa como se\u00f1al celular para regular el metabolismo y optimizar la energ\u00eda. Basado en evidencia precl\u00ednica, mejora la sensibilidad a la insulina, la adaptaci\u00f3n al estr\u00e9s y el rendimiento f\u00edsico relacionado con la edad.<\/span>[\/descripcion_corta_producto]\n[alerta_investigacion titulodisclaimer=\"Producto solo para uso investigativo\"]<span style=\"font-size: 16px;\">Producto de uso exclusivo para investigaci\u00f3n. La informaci\u00f3n sobre este producto no ha sido evaluada por el INVIMA, la FDA ni otras autoridades regulatorias.<\/span>[\/alerta_investigacion]\n","protected":false},"featured_media":4180,"template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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